Know about “Botox resistance”. No matter how much you add, your skin still wrinkled. The effects may spread and you cannot use Botox.
A case study of a 47-year-old woman from Singapore who had developed botox resistance. She had been using high-dose BoNT-A consistently every 6 months for 3 years. *She then noticed that the effectiveness of the BoNT-A treatment was decreasing. With shorter duration of results and